Gamma-Renin

Gamma-renin
Identifiers
EC number 3.4.21.54
CAS number 85270-20-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Gamma-renin (EC 3.4.21.54) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Cleavage of the Leu-Leu bond in synthetic renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen

This enzyme is present in submandibular glands of male mice.

References

  1. ↑ Poe, M.; Wu, J.K.; Florance, J.R.; Rodkey, J.A.; Bennett, C.D.; Hoogsteen, K. (1983). "Purification and properties of renin and γ-renin from the mouse submaxillary gland". J. Biol. Chem. 258: 2209–2216. PMID 6337154.
  2. ↑ Drinkwater, C.C.; Evans, B.A.; Richards, R.I. (1988). "Sequence and expression of mouse γ-renin". J. Biol. Chem. 263: 8565–8568. PMID 3288617.
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