Mapp Biopharmaceutical

Mapp Biopharmaceutical
Key people
 President: Larry Zeitlin, CEO: Kevin Whaley[1]
Products Biopharmaceuticals
Subsidiaries LeafBio

Mapp Biopharmaceutical is an American pharmaceutical company based in San Diego, California. It is responsible for the research and development of ZMapp, a drug which is still under development, comprising three humanized monoclonal antibodies as a treatment for Ebola virus disease.[2][3] The drug was first tested in humans during the 2014 West Africa Ebola virus outbreak. The ZMapp drug is a result of the collaboration between Mapp Biopharmaceutical, LeafBio (the commercial arm of Mapp Biopharmaceutical),[4] Defyrus Inc. (Toronto), the U.S. government and the Public Health Agency of Canada.[2] The antibody work came out of research projects funded by Defense Advanced Research Projects Agency (DARPA) more than a decade ago,[5] and years of funding by the Public Health Agency of Canada.[6] ZMapp is manufactured in the tobacco plant Nicotiana benthamiana in the bioproduction process known as "pharming" by Kentucky BioProcessing, a subsidiary of Reynolds American.[7][8][9]


References

  1. ↑ "Ebola Drug Made From Tobacco Plant Saves U.S. Aid Workers". Bloomberg. August 5, 2014Add. Check date values in: |date= (help)
  2. 1 2 "ZMapp Information Sheet" (PDF). Mapp Biopharmaceutical.
  3. ↑ "Mystery Ebola virus serum manufactured by San Diego firm". Los Angeles Times. August 4, 2014.
  4. ↑ "LeafBio". Retrieved August 12, 2014.
  5. ↑ Robert Langreth, Caroline Chen, James Nash and John Lauerman (August 4, 2014). "Ebola Drug Made From Tobacco Plant Saves U.S. Aid Workers". BusinessWeek.
  6. ↑ Helen Branswell for The Canadian Press. Aug. 5, 2014 Experimental Ebola drug based on research discoveries from Canada's national lab
  7. ↑ Kroll, David (5 August 2014). "Ebola 'Secret Serum': Small Biopharma, The Army, And Big Tobacco". Forbes.
  8. ↑ Parshley, Lois (8 August 2014). "ZMapp: The Experimental Ebola Treatment Explained". Popular Science.
  9. ↑ Daniel, Fran (12 August 2014). "Ebola drug provided for two Americans by Reynolds American subsidiary". Winston-Salem Journal.
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