Mefruside

Mefruside
Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C03BA05 (WHO)
Legal status
Legal status	℞ (Prescription only)
Identifiers
IUPAC name 4-chloro-N¹-methyl-N¹-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide
CAS Number	7195-27-9^Y
PubChem (CID)	4047
ChemSpider	3907^N
UNII	X1NS9SNS92^Y
KEGG	D01877^Y
ECHA InfoCard	100.027.785
Chemical and physical data
Formula	C₁₃H₁₉ClN₂O₅S₂
Molar mass	382.88 g/mol
3D model (Jmol)	Interactive image
SMILES CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
InChI InChI=1S/C13H19ClN2O5S2/c1-13(6-3-7-21-13)9-16(2)23(19,20)10-4-5-11(14)12(8-10)22(15,17)18/h4-5,8H,3,6-7,9H2,1-2H3,(H2,15,17,18)^N Key:SMNOERSLNYGGOU-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Mefruside (INN) is a diuretic indicated for the treatment of edema and hypertension.^[1]

It was developed by Bayer A.G. and is sold under the tradename Baycaron.

References

↑ Allen HB, Lee DA (1973). "A general practice assessment of mefruside ('Baycaron') in the treatment of oedema and hypertension". Curr Med Res Opin. 1 (9): 547–53. doi:10.1185/03007997309111720. PMID 4779251.

CA inhibitors (at PT)	Acetazolamide

Loop (Na-K-Cl at AL)	Furosemide^# Bumetanide Etacrynic acid Etozolin Muzolimine Ozolinone Piretanide Tienilic acid Torasemide

Thiazides (Na-Cl at DCT, Calcium-sparing)	Altizide Bendroflumethiazide Chlorothiazide Cyclopenthiazide Cyclothiazide Epitizide Hydrochlorothiazide^# Hydroflumethiazide Mebutizide Methyclothiazide Polythiazide Trichlormethiazide

Thiazide-likes (primarily DCT)	Quinethazone Clopamide Chlortalidone Mefruside Clofenamide Metolazone Meticrane Xipamide Indapamide Clorexolone Fenquizone

ESC blockers	Amiloride^# Triamterene Benzamil

Aldosterone antagonists	Spirolactones: Spironolactone^# Eplerenone Potassium canrenoate Canrenone Non-steroidal: Finerenone

Other

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