Puerarin
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| Names | |
|---|---|
| IUPAC name
7-Hydroxy-3-(4-hydroxyphenyl)-8-[(3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one | |
| Other names
Daidzein-8-C-glucoside 7,4'-Dihydroxy-8-C-glucosylisoflavone | |
| Identifiers | |
3681-99-0  | |
| 3D model (Jmol) | Interactive image Interactive image |
| ChEMBL | ChEMBL486386 |
| ChemSpider | 4445119 |
| ECHA InfoCard | 100.130.674 |
| PubChem | 5486172 |
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| Properties | |
| C21H20O9 | |
| Molar mass | 416.38 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
Puerarin, one of several known isoflavones, is found in a number of plants and herbs, such as the root of Pueraria (Radix puerariae)[1] notably of the kudzu plant.
Puerarin is the 8-C-glucoside of daidzein.[2]
List of plants that contain the chemical
Notes and references
- ↑ Dennis K.Y. Yeunga, Susan W.S. Leung, Yan Chun Xua, Paul M. Vanhouttea and Ricky Y.K. Mana (2006). "Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery". European Journal of Pharmacology. 552 (1–3): 105–11. doi:10.1016/j.ejphar.2006.08.078. PMID 17027964.
- ↑ Overstreet DH, Kralic JE, Morrow AL, Ma ZZ, Zhang YW, Lee DY (2003). "NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists". Pharmacology, biochemistry, and behavior. 75 (3): 619–625. doi:10.1016/S0091-3057(03)00114-X. PMID 12895679.
- ↑ Wang, Lingzhao; Yang, BAO; Du, Xiuqiao; et al. (2009). "Investigation of supercritical fluid extraction of puerarin from Pueraria Lobata". Journal of Food Process Engineering. John Wiley & Sons. 32 (5): 682–691. doi:10.1111/j.1745-4530.2007.00238.x.
- ↑ Chen, Gang; Zhang, J; Ye, J; et al. (2001). "Determination of puerarin, daidzein and rutin in Pueraria lobata (Wild.) Ohwi by capillary electrophoresis with electrochemical detection". Journal of Chromatography A. Elsevier. 923 (1 – 2): 255–262. doi:10.1016/S0021-9673(01)00996-7. PMID 11510548.
- ↑ Kintzios, Spiridon; Makri, Olga; Pistola, Eleni; Matakiadis, Theodoros; Ping Shi, He; Economou, Athanassios; et al. (2004). "Scale-up production of puerarin from hairy roots of Pueraria phaseoloides in an airlift bioreactor". Biotechnology Letters. Springer. 26 (13): 1057–1059. doi:10.1023/B:BILE.0000032963.41208.e8. ISSN 0141-5492.
- ↑ Shi, H. P; S. Kintzies (2003). "Genetic transformation of Pueraria phaseoloides with Agrobacterium rhizogenes and puerarin production in hairy roots". Plant Cell Reports. Springer. 21 (11): 1103–1107. doi:10.1007/s00299-003-0633-6. ISSN 0721-7714.
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