Trypanocidal agent

A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites.^[1]

Examples include:^[2]

References

↑ Trypanocidal Agents at the US National Library of Medicine Medical Subject Headings (MeSH)
↑ MeSH list of agents 82014344
↑ GOBLE, F. C. (January 1950). "Chemotherapy of experimental trypanosomiasis; trypanocidal activity of certain bis (2-methyl-4-amino-6-quinolyl) amides and ethers". Journal of Pharmacology and Experimental Therapeutics. 98 (1): 49–61. PMID 15403620.

Cryptosporidiosis	thiazolides (nitazoxanide)

Isosporiasis	trimethoprim/sulfamethoxazole^#

Toxoplasmosis	pyrimethamine sulfadiazine

Individual
agents

Aminoquinolines	(4-): amodiaquine^# chloroquine^# hydroxychloroquine^# (8-): primaquine^# pamaquine^‡ tafenoquine^†

4-Methanolquinolines	mefloquine^# quinine^# quinidine

Other	lumefantrine + artemether^# halofantrine

DHFR inhibitors	pyrimethamine biguanides chlorproguanil proguanil^#

Sulfonamides	sulfadoxine sulfalene

Co-formulation	sulfadoxine/pyrimethamine (SP)^#

Other

Combi-
nations

Fixed-dose (co-formulated) ACTs	artemether/lumefantrine^# arterolane/piperaquine artesunate/amodiaquine (ASAQ) artesunate/mefloquine (ASMQ) artesunate/pyronaridine dihydroartemisinin/piperaquine

Other combinations (not co-formulated)	artesunate/mefloquine artesunate/SP quinine/clindamycin quinine/doxycycline quinine/tetracycline

This article is issued from Wikipedia - version of the 6/12/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.